Kulit akar pule (Alstonia scholaris)

Kenting roots contain indole alkaloids such as echitamine and echitenine, typically present in higher concentrations than in the stem. These compounds provide strong analgesic effects and also help lower blood pressure. In addition, triterpenoids like lupeol acetate and α-amyrin act as anti-inflammatory agents that effectively relieve chronic inflammation in the joints and internal organs. Its saponin and tannin content also functions as a natural blood cleanser and provides antiseptic effects on the digestive tract.

The root bark of this plant is known as a specialist remedy for rheumatism and bone pain, especially in Jamu tradition, as it is considered more effective than the stem bark for treating long-lasting, deep-seated pain. In addition, the root bark is used in traditional therapy to address swelling of the liver and spleen, particularly in chronic infections such as recurrent malaria. Its extract has a strong relaxing effect on blood vessels, helping to lower high blood pressure. Unlike the stem bark, which is more focused on reducing fever, the root bark is often used in small doses as a restorative tonic after severe illness, helping the body regain strength.